February 4, 2025

U.S. Securities and Exchange Commission
Division of Corporation Finance
100 F Street, N.E.
Washington, D.C. 20549

Attn.: Tim Buchmiller
  Office of Life Sciences

  Re: OS Therapies Incorporated
    Registration Statement on Form S-1 (No. 333-284631)

Ladies and Gentlemen:

OS Therapies Incorporated hereby requests that the effectiveness of the above-referenced Registration Statement be accelerated so that it will become effective at 4:30 p.m., Eastern time, on Thursday, February 6, 2025, or as soon as practicable thereafter.

  Very truly yours,
   
  OS Therapies Incorporated
   
   
  By:

/s/ Paul A. Romness

    Paul A. Romness
    President and Chief Executive Officer